Roxana (c. 340 – c. 310 BCE), daughter of Oxyartes, a Bactrian nobleman who served Bessus, the satrap of Bactria and Sogdia, was probably in her late teens or early twenties when she married Alexander the Great. She subsequently bore him a son, Alexander IV, but mother and son were poisoned on Cassander's orders around 310 BCE. See here for a more detailed biographical sketch.